Laboratory Diagnosis of SARS
Identifieur interne : 005266 ( Main/Exploration ); précédent : 005265; suivant : 005267Laboratory Diagnosis of SARS
Auteurs : Paul K. S. Chan [République populaire de Chine] ; Wing-Kin To [République populaire de Chine] ; King-Cheung Ng [République populaire de Chine] ; Rebecca K. Y. Lam [République populaire de Chine] ; Tak-Keung Ng [République populaire de Chine] ; Rickjason C. W. Chan [République populaire de Chine] ; Alan Wu [République populaire de Chine] ; Wai-Cho Yu [République populaire de Chine] ; Nelson Lee [République populaire de Chine] ; David S. C. Hui [République populaire de Chine] ; Sik-To Lai [République populaire de Chine] ; Ellis K. L. Hon [République populaire de Chine] ; Chi-Kong Li [République populaire de Chine] ; Joseph J. Y. Sung [République populaire de Chine] ; John S. Tam [République populaire de Chine]Source :
- Emerging Infectious Diseases [ 1080-6040 ] ; 2004.
Descripteurs français
- KwdFr :
- ARN viral (analyse), ARN viral (isolement et purification), Adolescent, Adulte, Adulte d'âge moyen, Appareil respiratoire (virologie), Enfant, Enfant d'âge préscolaire, Excrétion virale, Facteurs temps, Femelle, Flambées de maladies, Fèces (virologie), Hong Kong, Humains, Maladies transmissibles émergentes (diagnostic), Maladies transmissibles émergentes (virologie), Maladies transmissibles émergentes (épidémiologie), Mâle, RT-PCR, Sujet âgé, Sujet âgé de 80 ans ou plus, Syndrome respiratoire aigu sévère (diagnostic), Syndrome respiratoire aigu sévère (virologie), Syndrome respiratoire aigu sévère (épidémiologie), Techniques de laboratoire clinique, Urine (virologie), Virus du SRAS (), Virus du SRAS (génétique), Virus du SRAS (isolement et purification).
- MESH :
- analyse : ARN viral.
- diagnostic : Maladies transmissibles émergentes, Syndrome respiratoire aigu sévère.
- génétique : Virus du SRAS.
- isolement et purification : ARN viral, Virus du SRAS.
- virologie : Appareil respiratoire, Fèces, Maladies transmissibles émergentes, Syndrome respiratoire aigu sévère, Urine.
- épidémiologie : Maladies transmissibles émergentes, Syndrome respiratoire aigu sévère.
- Adolescent, Adulte, Adulte d'âge moyen, Enfant, Enfant d'âge préscolaire, Excrétion virale, Facteurs temps, Femelle, Flambées de maladies, Hong Kong, Humains, Mâle, RT-PCR, Sujet âgé, Sujet âgé de 80 ans ou plus, Techniques de laboratoire clinique, Virus du SRAS.
- Wicri :
- geographic : Hong Kong.
English descriptors
- KwdEn :
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Clinical Laboratory Techniques, Communicable Diseases, Emerging (diagnosis), Communicable Diseases, Emerging (epidemiology), Communicable Diseases, Emerging (virology), Disease Outbreaks, Feces (virology), Female, Hong Kong, Humans, Male, Middle Aged, RNA, Viral (analysis), RNA, Viral (isolation & purification), Respiratory System (virology), Reverse Transcriptase Polymerase Chain Reaction, SARS Virus (classification), SARS Virus (genetics), SARS Virus (isolation & purification), Severe Acute Respiratory Syndrome (diagnosis), Severe Acute Respiratory Syndrome (epidemiology), Severe Acute Respiratory Syndrome (virology), Time Factors, Urine (virology), Virus Shedding.
- MESH :
- chemical , analysis : RNA, Viral.
- chemical , isolation & purification : RNA, Viral.
- geographic : Hong Kong.
- classification : SARS Virus.
- diagnosis : Communicable Diseases, Emerging, Severe Acute Respiratory Syndrome.
- epidemiology : Communicable Diseases, Emerging, Severe Acute Respiratory Syndrome.
- genetics : SARS Virus.
- isolation & purification : SARS Virus.
- virology : Communicable Diseases, Emerging, Feces, Respiratory System, Severe Acute Respiratory Syndrome, Urine.
- Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Clinical Laboratory Techniques, Disease Outbreaks, Female, Humans, Male, Middle Aged, Reverse Transcriptase Polymerase Chain Reaction, Time Factors, Virus Shedding.
Abstract
The virologic test results of 415 patients with severe acute respiratory syndrome (SARS) were examined. The peak detection rate for SARS-associated coronavirus occurred at week 2 after illness onset for respiratory specimens, at weeks 2 to 3 for stool or rectal swab specimens, and at week 4 for urine specimens. The latest stool sample that was positive by reverse transcription–polymerase chain reaction (RT-PCR) was collected on day 75 while the patient was receiving intensive care. Tracheal aspirate and stool samples had a higher diagnostic yield (RT-PCR average positive rate for first 2 weeks: 66.7% and 56.5%, respectively). Pooled throat and nasal swabs, rectal swab, nasal swab, throat swab, and nasopharyngeal aspirate specimens provided a moderate yield (29.7%–40.0%), whereas throat washing and urine specimens showed a lower yield (17.3% and 4.5%). The collection procedures for stool and pooled nasal and throat swab specimens were the least likely to transmit infection, and the combination gave the highest yield for coronavirus detection by RT-PCR. Positive virologic test results in patient groups were associated with mechanical ventilation or death (p < 0.001), suggesting a correlation between viral load and disease severity.
Url:
DOI: 10.3201/eid1005.030682
PubMed: 15200815
PubMed Central: 3323215
Affiliations:
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Le document en format XML
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S." last="Chan">Paul K. S. Chan</name><affiliation wicri:level="4"><nlm:aff id="aff1">The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="To, Wing Kin" sort="To, Wing Kin" uniqKey="To W" first="Wing-Kin" last="To">Wing-Kin To</name><affiliation wicri:level="1"><nlm:aff id="aff2">Princess Margaret Hospital, Kowloon, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Princess Margaret Hospital, Kowloon, Hong Kong SAR</wicri:regionArea><wicri:noRegion>Hong Kong SAR</wicri:noRegion></affiliation></author><author><name sortKey="Ng, King Cheung" sort="Ng, King Cheung" uniqKey="Ng K" first="King-Cheung" last="Ng">King-Cheung Ng</name><affiliation wicri:level="4"><nlm:aff id="aff1">The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Lam, Rebecca K Y" sort="Lam, Rebecca K Y" uniqKey="Lam R" first="Rebecca K. Y." last="Lam">Rebecca K. Y. Lam</name><affiliation wicri:level="4"><nlm:aff id="aff1">The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Ng, Tak Keung" sort="Ng, Tak Keung" uniqKey="Ng T" first="Tak-Keung" last="Ng">Tak-Keung Ng</name><affiliation wicri:level="1"><nlm:aff id="aff2">Princess Margaret Hospital, Kowloon, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Princess Margaret Hospital, Kowloon, Hong Kong SAR</wicri:regionArea><wicri:noRegion>Hong Kong SAR</wicri:noRegion></affiliation></author><author><name sortKey="Chan, Rickjason C W" sort="Chan, Rickjason C W" uniqKey="Chan R" first="Rickjason C. W." last="Chan">Rickjason C. W. Chan</name><affiliation wicri:level="4"><nlm:aff id="aff1">The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Wu, Alan" sort="Wu, Alan" uniqKey="Wu A" first="Alan" last="Wu">Alan Wu</name><affiliation wicri:level="4"><nlm:aff id="aff1">The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Yu, Wai Cho" sort="Yu, Wai Cho" uniqKey="Yu W" first="Wai-Cho" last="Yu">Wai-Cho Yu</name><affiliation wicri:level="1"><nlm:aff id="aff2">Princess Margaret Hospital, Kowloon, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Princess Margaret Hospital, Kowloon, Hong Kong SAR</wicri:regionArea><wicri:noRegion>Hong Kong SAR</wicri:noRegion></affiliation></author><author><name sortKey="Lee, Nelson" sort="Lee, Nelson" uniqKey="Lee N" first="Nelson" last="Lee">Nelson Lee</name><affiliation wicri:level="4"><nlm:aff id="aff1">The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Hui, David S C" sort="Hui, David S C" uniqKey="Hui D" first="David S. C." last="Hui">David S. C. Hui</name><affiliation wicri:level="4"><nlm:aff id="aff1">The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Lai, Sik To" sort="Lai, Sik To" uniqKey="Lai S" first="Sik-To" last="Lai">Sik-To Lai</name><affiliation wicri:level="1"><nlm:aff id="aff2">Princess Margaret Hospital, Kowloon, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Princess Margaret Hospital, Kowloon, Hong Kong SAR</wicri:regionArea><wicri:noRegion>Hong Kong SAR</wicri:noRegion></affiliation></author><author><name sortKey="Hon, Ellis K L" sort="Hon, Ellis K L" uniqKey="Hon E" first="Ellis K. L." last="Hon">Ellis K. L. Hon</name><affiliation wicri:level="4"><nlm:aff id="aff1">The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Li, Chi Kong" sort="Li, Chi Kong" uniqKey="Li C" first="Chi-Kong" last="Li">Chi-Kong Li</name><affiliation wicri:level="4"><nlm:aff id="aff1">The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Sung, Joseph J Y" sort="Sung, Joseph J Y" uniqKey="Sung J" first="Joseph J. Y." last="Sung">Joseph J. Y. Sung</name><affiliation wicri:level="4"><nlm:aff id="aff1">The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Tam, John S" sort="Tam, John S" uniqKey="Tam J" first="John S." last="Tam">John S. Tam</name><affiliation wicri:level="4"><nlm:aff id="aff1">The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author></analytic><series><title level="j">Emerging Infectious Diseases</title><idno type="ISSN">1080-6040</idno><idno type="eISSN">1080-6059</idno><imprint><date when="2004">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Child</term><term>Child, Preschool</term><term>Clinical Laboratory Techniques</term><term>Communicable Diseases, Emerging (diagnosis)</term><term>Communicable Diseases, Emerging (epidemiology)</term><term>Communicable Diseases, Emerging (virology)</term><term>Disease Outbreaks</term><term>Feces (virology)</term><term>Female</term><term>Hong Kong</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>RNA, Viral (analysis)</term><term>RNA, Viral (isolation & purification)</term><term>Respiratory System (virology)</term><term>Reverse Transcriptase Polymerase Chain Reaction</term><term>SARS Virus (classification)</term><term>SARS Virus (genetics)</term><term>SARS Virus (isolation & purification)</term><term>Severe Acute Respiratory Syndrome (diagnosis)</term><term>Severe Acute Respiratory Syndrome (epidemiology)</term><term>Severe Acute Respiratory Syndrome (virology)</term><term>Time Factors</term><term>Urine (virology)</term><term>Virus Shedding</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN viral (analyse)</term><term>ARN viral (isolement et purification)</term><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Appareil respiratoire (virologie)</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Excrétion virale</term><term>Facteurs temps</term><term>Femelle</term><term>Flambées de maladies</term><term>Fèces (virologie)</term><term>Hong Kong</term><term>Humains</term><term>Maladies transmissibles émergentes (diagnostic)</term><term>Maladies transmissibles émergentes (virologie)</term><term>Maladies transmissibles émergentes (épidémiologie)</term><term>Mâle</term><term>RT-PCR</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Syndrome respiratoire aigu sévère (diagnostic)</term><term>Syndrome respiratoire aigu sévère (virologie)</term><term>Syndrome respiratoire aigu sévère (épidémiologie)</term><term>Techniques de laboratoire clinique</term><term>Urine (virologie)</term><term>Virus du SRAS ()</term><term>Virus du SRAS (génétique)</term><term>Virus du SRAS (isolement et purification)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>RNA, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="isolation & purification" xml:lang="en"><term>RNA, Viral</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Hong Kong</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>ARN viral</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Communicable Diseases, Emerging</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Maladies transmissibles émergentes</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Communicable Diseases, Emerging</term><term>Severe Acute Respiratory Syndrome</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>SARS Virus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>ARN viral</term><term>Virus du SRAS</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Appareil respiratoire</term><term>Fèces</term><term>Maladies transmissibles émergentes</term><term>Syndrome respiratoire aigu sévère</term><term>Urine</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Communicable Diseases, Emerging</term><term>Feces</term><term>Respiratory System</term><term>Severe Acute Respiratory Syndrome</term><term>Urine</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Maladies transmissibles émergentes</term><term>Syndrome respiratoire aigu sévère</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Child</term><term>Child, Preschool</term><term>Clinical Laboratory Techniques</term><term>Disease Outbreaks</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Reverse Transcriptase Polymerase Chain Reaction</term><term>Time Factors</term><term>Virus Shedding</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Adulte</term><term>Adulte d'âge moyen</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Excrétion virale</term><term>Facteurs temps</term><term>Femelle</term><term>Flambées de maladies</term><term>Hong Kong</term><term>Humains</term><term>Mâle</term><term>RT-PCR</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Techniques de laboratoire clinique</term><term>Virus du SRAS</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Hong Kong</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The virologic test results of 415 patients with severe acute respiratory syndrome (SARS) were examined. The peak detection rate for SARS-associated coronavirus occurred at week 2 after illness onset for respiratory specimens, at weeks 2 to 3 for stool or rectal swab specimens, and at week 4 for urine specimens. The latest stool sample that was positive by reverse transcription–polymerase chain reaction (RT-PCR) was collected on day 75 while the patient was receiving intensive care. Tracheal aspirate and stool samples had a higher diagnostic yield (RT-PCR average positive rate for first 2 weeks: 66.7% and 56.5%, respectively). Pooled throat and nasal swabs, rectal swab, nasal swab, throat swab, and nasopharyngeal aspirate specimens provided a moderate yield (29.7%–40.0%), whereas throat washing and urine specimens showed a lower yield (17.3% and 4.5%). The collection procedures for stool and pooled nasal and throat swab specimens were the least likely to transmit infection, and the combination gave the highest yield for coronavirus detection by RT-PCR. Positive virologic test results in patient groups were associated with mechanical ventilation or death (p < 0.001), suggesting a correlation between viral load and disease severity.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li></country><settlement><li>Sha Tin</li></settlement><orgName><li>Université chinoise de Hong Kong</li></orgName></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Chan, Paul K S" sort="Chan, Paul K S" uniqKey="Chan P" first="Paul K. S." last="Chan">Paul K. S. Chan</name></noRegion><name sortKey="Chan, Rickjason C W" sort="Chan, Rickjason C W" uniqKey="Chan R" first="Rickjason C. W." last="Chan">Rickjason C. W. Chan</name><name sortKey="Hon, Ellis K L" sort="Hon, Ellis K L" uniqKey="Hon E" first="Ellis K. L." last="Hon">Ellis K. L. Hon</name><name sortKey="Hui, David S C" sort="Hui, David S C" uniqKey="Hui D" first="David S. C." last="Hui">David S. C. Hui</name><name sortKey="Lai, Sik To" sort="Lai, Sik To" uniqKey="Lai S" first="Sik-To" last="Lai">Sik-To Lai</name><name sortKey="Lam, Rebecca K Y" sort="Lam, Rebecca K Y" uniqKey="Lam R" first="Rebecca K. Y." last="Lam">Rebecca K. Y. Lam</name><name sortKey="Lee, Nelson" sort="Lee, Nelson" uniqKey="Lee N" first="Nelson" last="Lee">Nelson Lee</name><name sortKey="Li, Chi Kong" sort="Li, Chi Kong" uniqKey="Li C" first="Chi-Kong" last="Li">Chi-Kong Li</name><name sortKey="Ng, King Cheung" sort="Ng, King Cheung" uniqKey="Ng K" first="King-Cheung" last="Ng">King-Cheung Ng</name><name sortKey="Ng, Tak Keung" sort="Ng, Tak Keung" uniqKey="Ng T" first="Tak-Keung" last="Ng">Tak-Keung Ng</name><name sortKey="Sung, Joseph J Y" sort="Sung, Joseph J Y" uniqKey="Sung J" first="Joseph J. Y." last="Sung">Joseph J. Y. Sung</name><name sortKey="Tam, John S" sort="Tam, John S" uniqKey="Tam J" first="John S." last="Tam">John S. Tam</name><name sortKey="To, Wing Kin" sort="To, Wing Kin" uniqKey="To W" first="Wing-Kin" last="To">Wing-Kin To</name><name sortKey="Wu, Alan" sort="Wu, Alan" uniqKey="Wu A" first="Alan" last="Wu">Alan Wu</name><name sortKey="Yu, Wai Cho" sort="Yu, Wai Cho" uniqKey="Yu W" first="Wai-Cho" last="Yu">Wai-Cho Yu</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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